Criterion A: Knowing and Understanding
i. Outline scientific knowledge · ii. Apply knowledge to familiar and unfamiliar situations · iii. Interpret information to make scientifically supported judgements
| Level | Strand i: Describing Knowledge | Strand ii: Solving Problems | Strand iii: Interpreting Information |
|---|---|---|---|
| 7–8 | Outline scientific knowledge related to cells, organelles, and reproductive cells. | Apply scientific knowledge to familiar and unfamiliar situations related to cell biology. | Analyse information to make scientifically supported judgements. |
| 5–6 | Describe cells and organelles with some scientific accuracy. | Apply knowledge to solve problems mostly in familiar contexts. | Interpret information and make judgements with some scientific justification. |
| 3–4 | State basic knowledge about cells and organelles. | Attempt to apply knowledge in familiar situations. | Identify some information and make simple judgements. |
| 1–2 | Name some parts of a cell with limited accuracy. | Make limited attempts to solve problems. | Identify limited information. |
The diagram below shows a typical animal cell with six labelled organelles (1–6). Complete the table by selecting the correct name and stating the function of each organelle.
| Organelle | Name | Function — what does it do? |
|---|---|---|
| 1 | ||
| 2 | ||
| 3 | ||
| 4 | ||
| 5 | ||
| 6 |
A scientist is studying cells found in a jungle soil sample. They zoom in on one cell under an electron microscope and write the following description in their lab notebook:
(a) Using the scientist's description, match each observation to the organelle it most likely refers to. Ai · 1–2
| Scientist's observation | Organelle it describes |
|---|---|
| "Large dark-staining body near the centre" | |
| "Small bean-shaped structures with inner folds" | |
| "Thin and flexible outer layer" | |
| "Dense granular fluid filling the cell" |
(b) Is this cell most likely from an animal, a plant, or could it be either? Tick one and explain your reasoning using evidence from the description. Ai · 3–4
Here are two specialised reproductive cells — the egg cell (ovum) and the sperm cell. Use a colour code in the boxes to match each cell to its correct description.
(b) Choose ONE cell. Outline how its structure helps it carry out its function. Aii · 5–6
Fertility clinics use In Vitro Fertilisation (IVF) — egg cells are collected from a woman, fertilised by sperm in a laboratory, and the resulting embryo is placed back into the uterus to develop. Scientists track how successful IVF is across different age groups.
IVF Success Rate by Age Group (HFEA, UK 2023)
| Age Group | Success Rate (%) | Cycles Recorded |
|---|---|---|
| Under 35 | 32 | 18,240 |
| 35 – 37 | 25 | 11,850 |
| 38 – 39 | 19 | 8,430 |
| 40 and above | 11 | 9,110 |
(a) Using the data table and bar chart, identify which age group has the highest IVF success rate. State the specific value, compare it to the lowest value, and describe the overall trend shown in the graph. Aiii · 7–8
(b) A 36-year-old patient tries IVF three separate times, each using a fresh egg cell. Using the data, calculate the probability that at least one attempt succeeds. Show your full working. Aii · 5–6
(c) Name the organelle that carries most of the genetic instructions that determine what the child looks like, and explain why the child will most closely resemble the intended mother and father — not the donor — even though the donor's egg cell was used. Aii · 7–8
Criterion D: Reflecting on the Impacts of Science
i. Summarise application of science · ii. Describe implications · iii. Apply scientific language · iv. Document sources
| Level | Strand i: Application | Strand ii: Implications | Strand iii: Language | Strand iv: Sources |
|---|---|---|---|---|
| 7–8 | Summarise how cell biology is applied to address a reproductive health issue. | Describe and summarise social, economic, ethical, or cultural implications. | Apply scientific language clearly and accurately throughout. | Document sources clearly and consistently. |
| 5–6 | Describe the application with some accuracy. | Identify and describe some implications. | Use some scientific language. | Document most sources. |
| 3–4 | State how science is applied with limited detail. | Identify one implication simply. | Use limited scientific language. | Document one source. |
| 1–2 | Make a basic statement about science and the topic. | Identify a basic implication. | Limited or no scientific language. | No sources documented. |
Access to reproductive technologies such as IVF depends on where people live, how much money they have, and their cultural beliefs. While science has made it possible to help people start families, these solutions are not equally available to everyone.
(a) State what happens when a sperm cell and an egg cell fuse during fertilisation. Use scientific vocabulary.
(b) Outline two ways scientists apply their understanding of egg and sperm cells to address infertility. Di · 5–6
Choose one person — Priya or Marcus.
Outline one effect or consequence of limited access to IVF for your chosen person in their daily life.
Select one scientific solution that could help your chosen person. Describe and summarise how this solution helps them.
Select the factor most closely related to your chosen person's barrier:
Describe one advantage and one disadvantage of your chosen scientific solution in relation to your chosen factor. Explain why each matters.
| What happens because of this solution? | Why does this matter? | |
|---|---|---|
| Advantage | ||
| Disadvantage |
Document sources used. Cite in MLA9 format.
Criterion A: Knowing and Understanding
i. Outline scientific knowledge · ii. Apply knowledge to familiar and unfamiliar situations · iii. Interpret information to make scientifically supported judgements
| Level | Strand i: Describing Knowledge | Strand ii: Solving Problems | Strand iii: Interpreting Information |
|---|---|---|---|
| 7–8 | Outline scientific knowledge related to cells, organelles, and specialised cells. | Apply scientific knowledge to familiar and unfamiliar situations related to cell biology. | Analyse information to make scientifically supported judgements. |
| 5–6 | Describe cells and organelles with some scientific accuracy. | Apply knowledge to solve problems mostly in familiar contexts. | Interpret information and make judgements with some justification. |
| 3–4 | State basic knowledge about cells and organelles. | Attempt to apply knowledge in familiar situations. | Identify some information and make simple judgements. |
| 1–2 | Name some parts of a cell with limited accuracy. | Make limited attempts to solve problems. | Identify limited information. |
The diagram below shows a typical plant cell taken from a leaf. Six organelles are labelled 1–6. Complete the table by selecting the correct name for each organelle and stating its function.
| Organelle | Name | Function — what does it do? |
|---|---|---|
| 1 | ||
| 2 | ||
| 3 | ||
| 4 | ||
| 5 | ||
| 6 |
A scientist is growing cells in a laboratory and writes the following observation in their notebook. Read it carefully.
(a) Select whether this cell is a plant cell or an animal cell.
(b) State two pieces of evidence from the description that support your answer. Ai · 3–4
How does the eye detect light? — Rod cells, Cone cells & Melanocytes
The back of your eye is lined with a thin layer called the retina. The retina contains two types of specialised cells that detect light — rod cells and cone cells. These cells convert light into electrical signals that travel to your brain, which interprets them as images.
| Cell / Term | What it does |
|---|---|
| Rod cell | Detects dim light — works in low light / darkness. Cannot detect colour. Long and thin shape, packed with a light-sensitive pigment called rhodopsin. |
| Cone cell | Detects colour — works best in bright light. Three types: red, green, blue. Cone-shaped. Concentrated in the centre of the retina (fovea). |
| Melanocyte | A specialised skin cell that produces melanin — a dark pigment that absorbs UV rays before they can damage DNA inside skin cells. |
| Retina | The light-sensitive layer at the back of the eye — contains millions of rod and cone cells. |
| Melanin | Dark pigment in skin cells that absorbs UV radiation, protecting the cell's DNA from damage. |
Cross-section of the human eye
Rod vs Cone — structure comparison
Watch these short videos — then answer Q3 and D·Q1
▶ How do our eyes work? (Kurzgesagt · ~5 min)
▶ Rod & Cone cells explained (BBC Bitesize · ~3 min)
Here are three specialised cells found in the human body. Use a colour code in the boxes to match each cell to its correct function.
(b) Choose ONE cell — rod cell, cone cell, or melanocyte. Outline how its structure helps it carry out its function. Aii · 5–6
Scientists study how UV radiation from the sun damages skin cells. The table below shows data from a study on UV damage and sunscreen use across different age groups.
| Age Group | % with UV skin damage (no sunscreen) | % with UV skin damage (with sunscreen) |
|---|---|---|
| Under 10 | 12% | 3% |
| 11–18 | 28% | 6% |
| 19–35 | 47% | 9% |
| 36–60 | 63% | 11% |
| 60+ | 81% | 14% |
(a) Using the data, identify which age group has the highest UV damage without sunscreen. State the specific value and compare it to the group with the lowest damage. Describe the overall trend. Aiii · 7–8
(b) Using the data, calculate how much sunscreen reduces UV skin damage in the 19–35 age group. Show your working and state whether you think sunscreen is an effective scientific solution. Aii · 5–6
(c) Context: Skin cells contain a protein called melanin produced by specialised cells called melanocytes. People with more melanin have darker skin and naturally more UV protection. However, scientists say everyone — regardless of skin tone — can develop UV-related cell damage over time. Some communities do not use sunscreen because of cost or the belief that darker skin does not need it.
Using your knowledge of cell biology, explain why scientists recommend sunscreen for all skin tones. In your answer, refer to what happens to the DNA inside skin cells when UV rays are not blocked. Aii · 7–8
Criterion D: Reflecting on the Impacts of Science
i. Summarise application of science · ii. Describe implications · iii. Apply scientific language · iv. Document sources
| Level | Strand i: Application | Strand ii: Implications | Strand iii: Language | Strand iv: Sources |
|---|---|---|---|---|
| 7–8 | Summarises clearly how cell biology is applied to address a real-world problem. | Describes and summarises social, economic, ethical or cultural implications with justification. | Applies scientific language clearly and accurately. | Documents sources clearly and consistently. |
| 5–6 | Describes the application with some accuracy. | Identifies and describes some implications with some explanation. | Uses some scientific language. | Documents most sources. |
| 3–4 | States how science is applied with limited detail. | Identifies one implication simply. | Uses limited scientific language. | Documents one source. |
| 1–2 | Makes a basic statement about science and the topic. | Identifies a basic implication. | Limited or no scientific language. | No sources. |
Access to science-based health solutions — like eye tests, sunscreen, and protective medicines — is not equal around the world. The science exists, but social, economic, and cultural factors mean not everyone can benefit from it.
(a) Using the information from the reading section above, state what rod cells and cone cells do in the eye. Then explain how scientists use this knowledge to create eye tests. (Hint: use the vocabulary table — specialised cells, retina, function, detect, dim light, colour)
(b) Outline two ways scientists apply their understanding of specialised cells to help address health problems related to sight or skin. Di · 5–6
Choose one person — Priya or Kofi.
Outline one effect or consequence of your chosen person's situation on their daily life. Use scientific ideas in your answer.
Select one scientific solution that could help your chosen person. Describe and summarise how this solution helps them and why it matters.
Select the factor most closely related to your chosen person's barrier:
Describe one advantage and one disadvantage of your chosen scientific solution in relation to your chosen factor. Explain why each matters.
| What happens because of this solution? | Why does this matter? | |
|---|---|---|
| Advantage | ||
| Disadvantage |
Document sources used. Cite in MLA9 format.